Abstract:F-, Cl-, SO42-, NO3- in road dust of Nanjing City were determined by ion chromatography. Samples were allowed to be analyzed by ion chromatography after passing through a 100 mesh sieve, extracting by vortex centrifugation three times，taking the supernatant by high-speed centrifugation and filtering by a 0.22 μm filter membrane. Samples after centrifugation were separated with IonPacTMAS 11-HC（250 mm×4 mm）chromatographic column. 25 mmol/L NaOH was selected as mobile phase and conductivity detector was adopted as the detection sensor. For 4 anions, the method showed good linearity over a wide analysis range (0.01-0.2 mg/L) with correlation coefficients greater than 0.999. The addition recoveries were in the range of between 87.4%～95.2%. This method provides as fast analysis speed and good precision. It is suitable for evaluating the levels of four inorganic anions in road dust of Nanjing urban area.