Abstract:A method for the determination of iron and zinc in meal compound minerals by ultrasonic acid extraction ICP-OES method was developed. 10% nitric acid was used as pretreatment reagent, using ultrasonic assisted extraction. The experimental conditions was optimized, the interference was eliminated. Some experiments including detection limit, precision and accuracy was performed. The detection limit of iron and zinc was 1mg/kg and 0.5mg/kg , while the linear range was 0 ~5.0 mg/L and the linear coefficient (r) is better than 0.995. The precision of the method (RSD %) were less than 5.0%. The determined iodine contents were in good agreement with the certified values. The recoveries of real samples are from 91.4% to 107.9%. The experiments showed that this method was sensitive, simple and rapid, and accurate for the determination of iron and zinc contents in meal compound minerals .