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| Interpretation and Comparison of Three Procedures for the Determination of Method Detection Limit |
| Received:April 22, 2015 Revised:May 19, 2015 |
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| DOI： |
| KeyWord:Analytical chemistry, Method detection limit;Evaluation procedure |
| Author | Institution |
| Li Yuwu |
国家环境分析测试中心 |
| Ren Lijun |
国家环境分析测试中心 |
| Wang Jingrui and Di Yian |
国家环境分析测试中心 |
| DiYi-an |
国家环境分析测试中心 |
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| Abstract: |
| There are some standard procedures for the determination of method detection limit (MDL) in literature. It is important and significant to guide testing laboratories understanding and applying these procedures for obtaining comparable method performance parameters such as MDL. In this paper, systemic analysis and summarization, presentation of their features, application scope, main points for understanding for these procedures and comparison of different determination methods for MDL were discussed based on real data sets from literature and author’s laboratory. The modified procedure is proposed for MDL determination for different laboratory requirement according to scientific and maneuverability principles. |
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